The legend of the Black Sabbath Ozzy Osbourne died at 76 with rare parkinson’s

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The legend of rock Ozzy Osbourne died Tuesday at 76 after having fought a rare form of Parkinson’s disease.
The main singer of Black Sabbath had been open to his condition for several years, chatting first during an appearance in “Good Morning America” by ABC in 2019.
He and his wife Sharon Osbourne revealed the diagnosis of Rock Star from PRKN-2, a genetic condition generally defined as Parkinson’s disease with early appearance which evolves more slowly.
Ozzy Osbourne died at 76
“I’m not good with the secrets,” said the singer. “I can’t go for a walk with it, because it’s like, I lacked excuses, you know?”
Osbourne confirmed with GMA that he had had a “bad fall” which had led to neck surgery and interference with its nerves.

Singer Ozzy Osbourne occurs in the NFL match between the Buffalo Bills and the Los Angeles Rams on September 8, 2022 at the Sofi stadium in Inglewood, California. Osbourne died Tuesday at 76 after fighting a rare form of Parkinson’s disease. (Brian Rothmuller / Icon Sportswire via Getty Images)
The rocker took a while to perform to manage his health complications, but a few weeks before his death, he went on the stage last time for the performance “Back to the Beginning” by Black Sabbath on July 5 in Birmingham, in England.
What causes the Parkinson?
Dr. Brandon Crawford, a functional development neurologist in Cedar Park, Texas, and co-founder of the Austin Neurosolution center, noted that Parkinson’s disease can affect everyone differently.
Progressive neurodegenerative disorder has an impact on the brain area called the me utécephalus, which produces chemical dopamine.
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Dopamine is known to promote happiness, but it also motivates the body to move and think.
About 10% to 15% of Parkinson cases are “clearly linked” to genetics, noted Crawford, while the majority is due to a combination of light genetic sensitivity and environmental triggers.

Parkinson’s is a progressive neurodegenerative disorder that has an impact on the area of the brain called mesencephalon, which produces the dopamine neurotransmitter. (istock)
“Things like toxins, head trauma, sleep disturbances or chronic inflammation think of the balance of diseases,” Crawford, who has not treated Osbourne, in Fox News Digital.
Parkinson patients generally note a physical slowdown and an inability to move their bodies. Some will first discover tremors, which Crawford called a “characteristic sign”, often starting in your hands.
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The disease can also cause digestive complications, such as constipation, inflamed intestine or general intestinal problems. Cognitive decline is also a “major component” in the development of Parkinson, noted the doctor.
“Dopamine moves from the average brain in the frontal lobe, and that gives us our ability to think,” said Crawford. “This gives us a lot of our executive skills. And so that cognitive capacity begins to decrease.”

Flowers, notes and floral tributes placed on the black Sabbat Pont bench are seen in Birmingham, in the United Kingdom, on July 24, 2025, in memory of Ozzy Osbourne. (Ioannis Alexopoulos / Anadolu via Getty Images)
Patients can also notice slow speech and deregulated moods, often with signs of depression or a general lack of motivation.
“It is beyond the simple tail of tremors or slowdown in movements,” said Crawford. “This neurodegenerative disease is really starting to have an impact on someone’s life.”
Disease management
Although there is no remedy for Parkinson, it can be managed with dopamine agonists (drugs that imitate dopamine) and other stimulants that can stabilize symptoms for a limited period.
There may be “moments of clarity” and a better movement, said Crawford, “but while these drugs are starting to decline, everything comes back in a way.”

Ozzy Osbourne and Sharon Osbourne attend the pre-grammy gala on January 25, 2020 in Beverly Hills, California. Sharon Osbourne described the state of her husband during a 2019 interview with GMA, explaining how several good days are followed by “a very bad day”. (Alberto E. Rodriguez / Getty Images for the Registration Academy)
Sharon Osbourne described the state of her husband during the interview with GMA, explaining how several good days were often followed by “a very bad day”.
In 2024, during an episode of his program Siriusxm “Ozzy Speaks”, with the co-host Billy Morrison, the singer shared details on stem cell treatments for his condition, which he would have received for several years.
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Kelly Osbourne, Ozzy’s daughter, commented in an interview in 2020 with Cell4life, a stem cell based in the United Kingdom, that her father’s progress after a single treatment was “breathtaking”.
“He wants to get up. He wants to do things. He wants to be part of the world again,” she said. “He works better. He speaks better. His symptoms decrease. He strengthens the muscular strength he needs.”
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Stem cell therapy for Parkinson’s disease could replace the dopaminergic neurons lost in degeneration, according to mass general Brigham.
The hospital system announced the FDA approval of a phase 1 clinical trial for therapy in March.
Environmental factors
According to Crawford, the lifestyle of the Rock Star Star of the Rock Star of Ozzy Osbourne probably did not help the development of his condition, according to Crawford.
Circadian disturbances can be a major puree of Parkinson, because staying late at night in artificial lighting and meal consumption outside of a normal schedule can be harmful to the brain.

According to a doctor. (Getty Images)
“When the sun sets, our retinas, our brain, all our biology, are not designed to have this high frequency luminous stimulus,” he told Fox News Digital. “Several studies show that this type of exhibition … can disrupt this circadian biology.”
These factors can also change the microbiome, intestinal function, neurotransmitters’ production, liver function, detoxification paths and stem cell migration, and can also promote chronic inflammation, warned the doctor.
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For someone like Ozzy Osbourne who has experienced a lifestyle that probably does not consider “natural rhythms”, there may be a higher risk of other conditions, such as Alzheimer’s disease or heart disease, according to the expert.
Other lifestyle factors that could have led to the diagnosis of Osbourne by Parkinson include the constant presence of strong music, drug addiction and head of head, said Crawford.

Ozzy Osbourne performs on stage with Jake E. Lee. The lifestyle factors that could have led to the diagnosis of Parkinson of Osbourne include the constant presence of strong music, drug addiction and head of head, said a doctor. (Phil Dent / Redferns; Getty Images)
“It will create a repeated head trauma … If you are going to be up there by constantly shaking this brain in your head, it is literally like a bowl full of jelly,” he said.
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In addition to strong music, studies have shown that long -term exposure to heavy metals in the environment of a rock star – such as mercury, manganese and lead – could lead to an increased risk of Parkinson.
“While you are traveling around the world, you are staying in older places or use old equipment in a badly ventilated area,” said Crawford. “All these things are starting to add up.”