The smell of ear wax could provide an early alert sign of Parkinson’s disease

Ear wax can provide an unexpected early warning from Parkinson’s disease (PD), according to new research.

In particular, its smell could help clinicians detect the progressive disorder of the neurological movement, noted researchers in the study, which was published in the journal Analytical Chemistry.

According to health experts, bradykinesis (slow motion) and changes

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The study suggested that the volatile organic compounds (VOC) – which are released by sebum (oily secretions that help lubricate and protect the skin) in the ear wax of Parkinson – have a certain distinctive odor.

The smell is the result of systemic inflammation, neurodegeneration and oxidative stress linked to the progression of the disease, as indicated in the report of the American Chemical Society.

Ear wax can provide an unexpected early warning from Parkinson’s disease, according to new research. (istock)

“There is evidence that patients with Parkinson’s disease produce excess sebum, and other research groups have shown that there are special chemical profiles from this sebum compared to DP patients,” said Dr. Joohi Jimenez-Shahed, Medical Director of Medicine Disorders in New York, told Fox News Digital.

(Jimenez-Shahed was not affiliated with the study.)

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In this recent study, researchers in China analyzed the wax cleared from the ear canals of 209 participants, of which 108 had been diagnosed with Parkinson.

Using specialized methods to analyze chemicals in wax, researchers found that four of the VOCs in people with disease were significantly different from those who had not been diagnosed, detailed the study.

The study suggested that the volatile organic compounds (VOC) – which are released by sebum (oily secretions that help lubricate and protect the skin) in the ear wax of Parkinson – have a certain distinctive odor. (istock)

They concluded that four VOCs-Ethylbenzene, 4-Ethyltolène, Pentanal and 2-Pentadecyl-1,3-Dioxolane)-can be used as potential biomarkers for PD.

The researchers used the ear wax data collected to form an artificial intelligence alfactory system (AIO), a technology that uses sensors to simulate human smell to detect and analyze VOCs.

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According to the report, the AIO system has shown 94% precision with people’s ear wax samples with and without parkinson.

Study authors suggested that the AIO system could possibly be used as a first -line screening tool for early Parkinson detection, allowing the disease before.

According to health experts, bradykinesis (slow motion) and changes (istock)

Most current treatments only manage the symptoms and help maintain quality of life, but do not stop or reversing the disease, making early diagnosis and treatment vital, according to the National Institute of Neurological Disorders and Cerebral Vascular Accidents (NINS).

The report also noted that current tests for Parkinson – such as imaging studies and clinical rating scales – can be expensive and subjective.

This potential detection system could provide an easy and inexpensive way to test the disease, although experts have stressed that more tests are required.

Future limitations and research

The study was carried out on a small scale in a single clinic in China, according to Hao Dong, one of the authors of the study of the Research Center for the fundamental studies of Frontier in China.

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“The next step is to carry out additional research at different stages of the disease, in several research centers and between several ethnic groups, in order to determine whether this method has greater practical application value,” Dong said in a press release.

Jimenez-Shahed noted that, ideally, this new method could serve as an early diagnostic test, potentially easier than using vertebral fluid, skin biopsies or specialized analyzes.

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The above expert, who is also an associate professor of neurology and neurosurgery at the Icahn Medicine School of Mont Sinai, warned that the particular profiles of the earwells of ear was reported in the recent study may differ from the results of other studies.

“There must be a replication and / or expansion of the sample size before determining the specific diagnostic potential of a test like this,” he added.

Those who are concerned about Parkinson’s potential risk should consult a neurologist or a specialist in movement problems, advised Jimenez-Shahed.

A specialist can carefully detect the individual for early alert panels and determine the need for additional testing or diagnostic treatments.

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The study was funded by the National Natural Sciences Foundation of Science, Pioneer and leader in the OIE R&D program in the Zhejiang province and basic research funds for central universities.

Fox News Digital contacted study authors for additional comments.